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Computational Biologist III/Sr. Computational Biologist, Bioinformatics and Biosecurity 49 views

Remote/Boston, MA

Ginkgo Bioworks is a publicly traded (NYSE: $DNA), high-growth biotechnology company based in Boston’s Seaport District, that is redesigning the living world to solve some of the globe’s growing challenges in health, energy, food, material, and more. Our mission to “make biology easier to engineer” is poised to disrupt multiple industries by leveraging our innovative data, automation, and scale capabilities in biological engineering. 
In response to the global COVID-19 pandemic, we have launched a new division: Concentric by Ginkgo. We firmly believe that testing is an essential requirement to re-open the economy as quickly and safely as possible. Concentric is the largest provider of K-12 COVID-19 testing. We currently run state-level K-12 testing programs in more than 10 states and some of the nation’s largest school districts. To date, Concentric has sequenced more than 10,000 samples from a variety of sample types, in support of public health. As we continue to scale Concentric by Ginkgo, our work is also evolving and expanding into new and exciting directions. 
We are seeking a motivated Computational Biologist, Bioinformatics and Biosecurity, to join our growing team and be a part of implementing innovative biosecurity solutions. Specifically, you bring subject matter expertise in synthetic biology, organism engineering, high throughput sequencing, and bioinformatics to help lead Concentrics growth in biosecurity through our growing biomonitoring program, as well as cell engineering programs. Your responsibilities will include not only analysis of sequencing data, but supporting long-term biosecurity initiatives within Concentrics Innovation Team including emergent cell engineering programs. As a Computational Biologist, you will interface with Concentric and key teams in the Ginkgo Bioworks Foundry to ensure program success through high quality deliverables and appropriately resourced activities. You are a cross-functional team player, bringing diverse perspectives to our interdisciplinary team, and poised to develop the future of biosecurity.


  • Provide technical direction and guidance on synthetic biology in the context of biosecurity and bio surveillance
  • Support efforts to deploy novel biosecurity technologies around cell engineering, bio surveillance, and new sequence based tools 
  • Work with Concentric and Foundry leads to scope, plan, and lead projects to develop and implement new biosecurity monitoring and sequencing tools 
  • Collaborate with Foundry operators on experimental design and analysis to optimize new analytic approaches using NGS technologies
  • Analyze sequencing data from multiple NGS technologies Analyze varied-omic data sets (genomics, transcriptomics, metagenomics, de novo genome assembly, etc.)
  • Interface with software engineers to create and implement NGS data analysis pipelines for production use
  • Monitor scientific literature for new methods and data analysis tools
  • Effectively communicate scientific results to technical and non-technical audiences
  • Measure and evaluate team performance with respect to the technical success of team projects, as well as the continued development of your high-performing team
  • Partner with our Business Development Team to identify and evaluate new project opportunities from both a technical and commercial perspective
  • Assist with shaping Ginkgo and Concentrics overall direction as a company and support its evolving needs, as necessary
  • Minimum Requirements

  • PhD with at least 3 years of experience in a relevant life science/computational biology field
  • Excellent project management skills, with the ability to oversee multiple simultaneous projects, meet deadlines, and collaborate with cross-functional teams
  • Proven track record of leading successful teams and mentoring multiple team members
  • Superb communication skills, with the ability to effectively convey project plans and complex technical details to a wide range of internal teams, executive leadership, and external customers
  • Ability to adapt to changing priorities and pivot as needed in a fast-paced environment
  • Preferred Capabilities and Experience

  • At least one year of industrial experience in synthetic biology/computational biology/bioinformatics
  • Direct sequencing and bioinformatics experience with varied pathogen types (e.g. viral, bacterial, fungal)
  • Experience with engineering one or more bacterial, yeast, or filamentous fungal species; wet lab experience is a plus
  • First-hand technical experience in at least two of the following disciplines:  synthetic biology, bioinformatics, sequence analysis, comparative genomics, phylogenetics, Next Generation Sequencing (NGS) analysis, statistics, probabilistic modeling, machine learning, population genetics, metabolic engineering, and quantitative modeling of biological systems
  • Experience with many or all of the following:  Python, bash/unix scripting, Snakemake, Nextflow, airflow, CWL, relational databases (SQL), GraphQL, distributed computing (AWS/Google Cloud), Docker, software version control (git)
  • Formal project management training is a plus
  • Note on culture: Concentric by Ginkgo is a high energy, positive and fast paced environment where new challenges and opportunities arise every day, so this opportunity is ideal for people who thrive in those kinds of environments, and for people who like lots of variety in their day. There are lots of opportunities to learn and grow. The team is motivated by doing high impact work in service to society. To get a sense of the culture at Ginkgo, read some articles in Grow by Ginkgo, the company magazine we produce, which tells the story of synthetic biology in a Ginkgo-authentic way.
    To learn more about Ginkgo, check out some recent press:
    We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.  
    We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.
    It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.
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    Company Information
    • Active Jobs 101 Jobs
    • Company Address 27 Drydock Avenue, 8th Floor Boston, MA 02210
    • City Boston
    • Location Massachusetts
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