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Protein Biochemist 61 views

Boston, MA

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms.
Whether they are the final product or the catalysts for an engineered process, proteins lie at the center of many strain engineering efforts. The Protein Characterization team operates at the intersection of Protein Engineering, High-throughput Screening, Fermentation, and Downstream Processing to help assess the proteins that are so central to the mission at Ginkgo.
As a Protein Biochemist, you will have the opportunity to use your biochemistry expertise at a growing company in a state-of-the-art facility. Your work at Ginkgo will require the purification of heterologous protein from diverse sources, including microbial and mammalian expression systems. In addition to purifying proteins from diverse sources, the proteins you will work on run the gamut, including biosynthetic enzymes, molecular biology reagents, food proteins, and more. Your work will also include protein characterization, with a focus on enzyme kinetic characterization. Ginkgo is particularly interested in translating traditional biochemical and biophysical techniques into higher throughput methods using the array of technology available at Ginkgo and on the market. 


  • Purify enzyme and non-enzyme proteins at small to medium scales to support strain engineering efforts at Ginkgo
  • Develop diverse methods for continuous and discontinuous (quench-based) kinetics assays
  • Translate kinetics and biophysical assays from traditional benchtop set ups to automated liquid handlers to develop higher throughput methodologies
  • Perform electrophoresis, light-scattering, etc. to assess protein purity and biophysical characteristics
  • Write Standard Operating Procedures (SOPs) and maintain a high-quality Electronic Laboratory Notebook (ELN)
  • Prepare presentations and present data to internal and external Ginkgo partners
  • Work with teams with diverse scientific backgrounds and varying biochemistry experience levels
  • Desired Experience and Capabilities

  • PhD or equivalent in molecular biology, biochemistry, bioengineering, chemical engineering, biophysics, or related field
  • 2+ years industry experience
  • Hands on experience with AKTA FPLC systems for protein purification and purification optimization
  • Demonstrated experience developing Michaelis-Menten kinetics assays
  • Interest in high-throughput methods for protein purification and characterization
  • Experience with biophysical characterization techniques (SLS, DLS, Tm, SPR, aggregation assays)
  • Prior experience with crystallography is a plus
  • To learn more about Ginkgo, check out some recent press:
    We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.  
    We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.
    It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.

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    Company Information
    • Active Jobs 133 Jobs
    • Company Address 27 Drydock Avenue, 8th Floor Boston, MA 02210
    • City Boston
    • Location Massachusetts
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