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Scientist, Mammalian Gene Therapy 135 views

Job Expired

Boston, MA

Ginkgo’s mission is to make biology easier to engineer. We are constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms.
Ginkgo is continuously crossing new frontiers of biological engineering and we have a record of delivering what was, until recently, thought impossible. Now, our expansion into mammalian cell engineering promises to push our boundaries even further, and so we’re looking for pioneering engineers to make Ginkgo’s new mammalian cell foundry a success.
While cell and gene therapies have seen remarkable success in the clinic, we are at the dawn of a new age in our ability to precisely control gene expression. To do this well, we need to build out our mammalian editing platform with your help. We have a strong microbial platform that serves diverse hosts, and we need you to help us scale what we have to include cell therapy and viral gene therapy in eukaryotic cell lines. Should we build a new version, adapt what we have or acquire new technology? We’ll need your experience and insight to show us the way.
You’ll need to work collaboratively with a variety of folks to get this done, including our amazing software engineers, automation engineers and junior researchers. You’ll need excellent written and oral communication skills to ensure that your ideas are well understood by a diverse audience. We are excited to have you onboard!

Responsibilities

  • Build/adapt NGS library prep workflows to support mammalian cell engineering needs including gene knockout, gene knockin, off target and insertion site analysis
  • Design and build pooled libraries for improving AAV production
  • Understand commercial needs and technical feasibility for meeting ongoing needs of many projects
  • Resolve technical challenges between what you know is feasible and what the cell engineering team needs
  • Empower several peers and junior researchers to carry out excellent and robust work on the platform that you build
  • Build the plane while flying it: deliver commercial results while building out the platform
  • Some specific examples include pooled strain construction methods and high throughput analysis of off target genetic editing events
  • Requirements

  • PhD or equivalent or 5+ years of industrial or post-graduate experience in mammalian cell engineering
  • Prior experience in one or more of the following: high throughput pipelines, laboratory automation, software engineering, NGS, DNA synthesis and assembly, mammalian genome engineering, AAV packaging and production
  • Great people management and teaching abilities
  • Excellent written communication skills
  • To learn more about Ginkgo, check out some recent press:
    We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.  
    We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.
    It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.

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    Company Information
    • Active Jobs 99 Jobs
    • Company Address 27 Drydock Avenue, 8th Floor Boston, MA 02210
    • City Boston
    • Location Massachusetts
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