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Senior Technical Director, Microbial Engineering 9 views

Boston, MA

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. 
Our Codebase team of Organism Engineers (OEs) is the core of Ginkgo’s strain engineering platform. We believe biology is a unique engineering substrate that comes pre-loaded with startlingly brilliant code we didn’t write. Enabled by our high-throughput foundry, we study and design the most efficient way to create a new organism using the most advanced molecular biology techniques. We also employ various -omics technologies for understanding, troubleshooting, and debottlenecking our designed systems. 
We are looking for a talented Principal Organism Engineer to provide technical guidance in engineering both model and non-model microbial strains for both novel biosynthetic pathway engineering as well as improving the efficiency of these pathways in existing commercial strains. With your depth of experience in strain engineering, you will be responsible for leading projects tasked with both engineering strains that express novel metabolic pathways and ensuring that these strains meet commercial performance targets. You will also be responsible for implementing new enabling technologies for metabolic engineering across the teams you are a part of and throughout Ginkgo’s foundry.


  • Provide technical direction and guidance on synthetic biology, metabolic design and metabolic engineering of target host organisms to your team to ensure project success
  • Analyze host organism physiology to identify bottlenecks limiting organism performance and re-design organisms to alleviate bottlenecks and improve performance 
  • Collaborate with customers and internal process development teams to establish commercial-scale processes based upon novel strains developed by your team
  • Lead efforts to identify and develop novel technology around adapting new host organisms and new genetic tools to foundry operations 
  • Measure and evaluate team performance with respect to the technical success of team projects, as well as the continued development of high-performing teams
  • Manage projects plans and team resources across your team and communicate project and team performance to Ginkgo leadership and external customers
  • Mentor and coach Codebase teammates on metabolic engineering strategies and techniques
  • Assist Commercial Operations in evaluating new project opportunities from a technical perspective as well as proposing work plans, budgets and timelines. Also, provide customer updates on metabolic engineering progress and communicate Ginkgo’s unique offerings to current and potential customers
  • Assist with shaping Ginkgo’s overall direction as a company and support its evolving needs, as necessary
  • Desired Experience and Capabilities

  • PhD in microbiology, biochemistry, genetics, chemical or biological engineering or related field
  • At least 14 years of industrial research experience engineering microbial metabolism or developing novel synthetic biology tools in multiple microorganisms selected from yeasts, bacteria or filamentous fungi. Relevant academic experience will also be considered
  • Excellent project management skills, with the ability to oversee multiple simultaneous projects, meet deadlines, and collaborate with cross-functional teams
  • Proven track record of leading successful teams while mentoring, advising and managing multiple team members
  • Superb communication skills, with the ability to effectively convey project plans and complex technical details to a wide range of internal teams, executive leadership, and external customers
  • Enthusiasm for being a part of Ginkgo’s mission
  • To learn more about Ginkgo, check out some recent press:
    We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.  
    We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.
    It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.

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    • Active Jobs 101 Jobs
    • Company Address 27 Drydock Avenue, 8th Floor Boston, MA 02210
    • City Boston
    • Location Massachusetts
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